Not Yet RecruitingNot Applicable

Prognosis and Diagnosis of Acute Gastrointestinal Dysfunction in Cardiac Surgery Patients

Russia100 participantsStarted 2026-03-10

Plain-language summary

The purpose of this prospective observational clinical cohort study is to develop a scientifically based approach to the prediction and early diagnosis of intestinal dysfunction in cardiac surgery patients. The main questions that the study should answer: What are the main risk factors for the development of intestinal dysfunction? What specific and non-specific biomarkers can predict the development of intestinal dysfunction? The study participants will be monitored from the moment of hospitalization until the end of their stay in a medical facility

Who can participate

Age range

18 Years – 95 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Surgery on the heart and main vessels with a high risk of developing gastrointestinal dysfunction (according to literature data and our own retrospective study); * Patient's consent to participate in the study Exclusion Criteria: * Patient's refusal to participate in the study; * HIV infection in the patient; * Immunosuppressive therapy; * Oncological disease;

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Identification of markers of intestinal dysfunction:

Timeframe: During the first 24h after surgery for all patients. On the third, sixth and ninth day, if the patient stay in the ICU

The use of pharmacological stimulation of gastrointestinal motility

Timeframe: During the first 24h after surgery for all patients. On the third, sixth and ninth day, if the patient stay in the ICU

Trial details

NCT IDNCT07422246

SponsorPetrovsky National Research Centre of Surgery

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-09-01

Contact for this trial

Maxim A. Babaev

+7-916-026-9066 maxbabaev@mail.ru

View on ClinicalTrials.gov More Gastrointestinal Dysfunction trials

Plain-language summary

Who can participate

Age range

18 Years – 95 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Identification of markers of intestinal dysfunction:

Timeframe: During the first 24h after surgery for all patients. On the third, sixth and ninth day, if the patient stay in the ICU

The use of pharmacological stimulation of gastrointestinal motility

Timeframe: During the first 24h after surgery for all patients. On the third, sixth and ninth day, if the patient stay in the ICU