Management of Epistaxis Comparing Nasal Packing Versus Greater Palatine Foramen Block (NCT07421622) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Management of Epistaxis Comparing Nasal Packing Versus Greater Palatine Foramen Block
40 participantsStarted 2026-03-01
Plain-language summary
The goal of this pilot randomized controlled trial is to compare pain relief efficacy while using nasal packing versus greater palatine foramen block (GPFB) in the management of acute episodes of epistaxis. The main questions it aims to answer are: Does GPFB have less potential to inflict pain when dealing with hemostasis with epistaxis, utilizing a pre-validated 10-point visual analog scale (VAS)? Was hemostasis management more effective in either technique? Researchers will compare anterior nasal packing to greater palatine foramen block using 2% xylocaine with adrenaline.
Patients will receive any of the hemostatic interventions at the time of the acute epistaxis episode.
The questionnaire will be administered 24 hours post-intervention.
Who can participate
Age range
18 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Presentation with active anterior epistaxis
* Failure of initial conservative measures (e.g., nasal compression and topical vasoconstrictors)
* Ability to provide informed consent and those who consent for the study.
Exclusion Criteria:
* Suspected or confirmed posterior epistaxis
* Known bleeding disorders or platelet count \<50,000/mm³
* Use of anticoagulants with supratherapeutic INR
* Known allergy to local anaesthetic agents
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
● Pain intensity measured
Timeframe: 24 hours post intervention
Trial details
NCT IDNCT07421622
SponsorSheikh Zayed Federal Postgraduate Medical Institute