Not Yet RecruitingPhase 1/2

Antibacterial Effect and Post-operative Pain Following Various Techniques of Intracanal Heating of NaOCL

36 participantsStarted 2026-02-10

Plain-language summary

The goal of this clinical trial is to is to assess the antibacterial effect of sodium hypochlorite heated inside root canals of necrotic teeth using various activation techniques The main question it aims to answer is: Does the antibacterial effect vary following various standardized techniques of intracanal heating of sodium hypochlorite in endodontic treatment?

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: For patients: * adult male or female patients * medically free. For selected teeth: * asymptomatic necrotic single rooted teeth * teeth with mature root * restorable teeth. Exclusion Criteria: For patients: * Patients with dental related symptoms * patients with chronic or systemic diseases * pregnant females. For selected teeth: * multirooted teeth * vital teeth * teeth with incompletely formed roots * teeth with internal or external resorption * previously root canal treated teeth

What they're measuring

Bacterial reduction

Timeframe: after treatment, samples are sent to microbiology lab and bacterial count is measured day 1 after treatment.

Trial details

NCT IDNCT07420920

SponsorMisr University for Science and Technology

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-01

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