RecruitingNot Applicable

Evaluation of the Synergistic Effect of Combining a Prebiotic and a Postbiotic on Intestinal Discomfort

Belgium140 participantsStarted 2026-03-16

Plain-language summary

This study aims to investigate the beneficial effects of the daily consumption of a synbiotic formulation-combining a prebiotic (Berberine, BBR) and a postbiotic (inactivated Bifidobacterium Longum, B.longum)-in adults experiencing intestinal discomfort.

Who can participate

Age range18 Years – 75 Years

SexALL

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Inclusion criteria

✓. Experience recurrent abdominal pain present for at least three months and occurring on a regular basis;
✓. The abdominal discomfort must have a low to moderate impact on quality of life;
✓. In addition, participants must report at least two of the following gastrointestinal symptoms:

What they're measuring

Change from baseline in the intensity and frequency of intestinal symptoms

Timeframe: Throughout the entire study, approximately during 10 months

Change from baseline in the intensity and frequency of intestinal symptoms

Timeframe: Throughout the entire study, approximately during 10 months

Trial details

NCT IDNCT07420231

SponsorUniversité Catholique de Louvain

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-10-24

Contact for this trial

Valerie Dormal, PhD

+32(0)10 47 93 05 valerie.dormal@uclouvain.be

View on ClinicalTrials.gov More Intestinal Discomfort trials