RecruitingNot Applicable

Point of Care Tests in the Management of Very Early Medical Abortion

Sweden, United Kingdom130 participantsStarted 2026-04-23

Plain-language summary

This study will investigate the use of a point of care test in patients who are having an abortion at a gestation of \<6 weeks (known as a very early medical abortion). These patients have pregnancy hormone level checked at Day 0 and Day 7 to see if treatment has worked. The investigators plan to use a point of care test machine to see if it is possible to check pregnancy hormone level earlier than Day 7.

Who can participate

Age range16 Years – 55 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Positive pregnancy test * Less than six weeks gestation based upon Last Menstrual Period (LMP) * No evidence of definite intrauterine pregnancy on ultrasound * No signs or symptoms or significant risk factors for ectopic * Wish to proceed to VEMA (Very Early Medical Abortion) * Available for usual clinical follow up * Willing to attend for serum Human Chorionic Gonadotropin (HCG) on two occasions Day 2-4 and Day 7 post mifepristone * Written informed consent Exclusion Criteria: * Pain and/or bleeding * Significant risk factors for ectopic (previous ectopic, sterilisation, tubal disease, intrauterine device in situ) * Suspicious features for ectopic on ultrasound (adnexal mass, moderate free fluid) * Unable to provide blood sample * Lack of Capacity to consent

What they're measuring

Sensitivity

Timeframe: Day 0, Day 2-4 and Day 7

Specificity

Timeframe: 7 days

Trial details

NCT IDNCT07417787

SponsorUniversity of Edinburgh

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-02

Contact for this trial

Jacqueline Quinn

+44 0131 536 1542 chalmers.research@ed.ac.uk

View on ClinicalTrials.gov More Abortion Early trials