RecruitingNot Applicable

Comparing PTeye-assisted Versus Conventional Total Thyroidectomy

Hong Kong210 participantsStarted 2025-09-16

Plain-language summary

This is a prospective, single-blinded, randomized controlled trial to evaluate whether PTeye™ can reduce post-operative hypoparathyroidism (PH). The study will enroll consecutive patients undergoing total thyroidectomy in a teritary endocrine surgery unit in Hong Kong, randomizing them into receiving conventional surgery versus PTeye™-assisted surgery. Subjects will be assigned to the two groups before surgery. Subjects will be under medical care as in usual practice.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients ≥18 years of age * Undergoing total thyroidectomy, or completion total thyroidectomy * Pre-operative serum adjusted calcium levels within normal ranges Exclusion Criteria: * Patients on pre-operative calcium or vitamin D supplements * Patients with pre-operative vitamin D deficiency, defined as serum vitamin D\<30nmol/L * Patients with untreated primary or secondary hyperparathyroidism * Patient with known non-surgical hypoparathyroidism diseases * Patients with estimated glomerular filtration rate \<30ml/1.73m2/min, on dialysis, or having a history of kidney transplant

What they're measuring

Rate of significant post-operative hypoparathyroidism (SPH) after total thyroidectomy (in %)

Timeframe: 6 months

Trial details

NCT IDNCT07416149

SponsorThe University of Hong Kong

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-10-31

Contact for this trial

Man Him, Matrix Fung, MBBS

+852 2255 4232 mmhfung@hku.hk

View on ClinicalTrials.gov More Hypocalcemia trials