The Effect of a Four-Week Hatha Yoga Intervention to Improve Quality of Life, Anxiety, and Depres… (NCT07415850) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The Effect of a Four-Week Hatha Yoga Intervention to Improve Quality of Life, Anxiety, and Depressive Symptoms in Individuals Undergoing Assisted Reproductive Technology (ART) Treatment
United States80 participantsStarted 2026-01-21
Plain-language summary
The goal of this clinical trial is to learn if a four-week yoga program works to improve quality of life in people undergoing IVF (In Vitro Fertilization). It will also learn if a four-week yoga program decreases anxiety and depression symptoms in people undergoing IVF.
The main questions it aims to answer are:
* Does a four-week yoga program effect quality of life, anxiety, and depression symptoms in people undergoing IVF?
* Do the effects vary by individual characteristics of the people in the study?
Researchers will compare the yoga intervention group to routine care as usual.
Participants will:
* Participate in a weekly virtual yoga class for four weeks (total of four yoga classes), or follow routine care as usual while undergoing IVF.
* Take three online surveys every 4 weeks.
* Be involved in the study for 8 weeks.
Who can participate
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 18 years of age or older
* Understand English
* Scheduled for or currently undergoing an IVF cycle
* Access to smartphone/computer/tablet and internet
* Have a valid working email address
Exclusion Criteria:
* Individuals who are Pregnant, or who become Pregnant during the study
* Individuals undergoing non-IVF cycles (i.e. intrauterine insemination)
* Individuals undergoing a frozen embryo transfer (FET) cycle
* Individuals who are currently regularly practicing yoga
* Individuals who score in the "severe depression" classification on the PHQ-9 (PHQ-9 score of 20-27)
* Individuals endorsing suicidal ideation (answering yes on #9 of PHQ-9).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change from Baseline in Fertility Quality of Life using the FertiQoL, a validated 24-item self-report questionnaire, measured at 4 weeks and 8 weeks.
Timeframe: From enrollment (Baseline) to the end of treatment at 8 weeks.
2
Change from Baseline in Anxiety symptom severity using the Hospital Anxiety and Depression Scale, Anxiety Subscale (HADS-A), measured at 4 weeks and 8 weeks.
Timeframe: From enrollment (Baseline) to the end of treatment at 8 weeks.
3
Change from Baseline in Depressive symptom severity using the Patient Health Questionnaire (PHQ-9), measured at 4 weeks and 8 weeks.
Timeframe: From enrollment (Baseline) to the end of treatment at 8 weeks.