Acute Effect of Apple Cider Vinegar on Postprandial Plasma Malondialdehyde in Adult With Obesity (NCT07414875) | Clinical Trial Compass
CompletedNot Applicable
Acute Effect of Apple Cider Vinegar on Postprandial Plasma Malondialdehyde in Adult With Obesity
Indonesia46 participantsStarted 2026-02-04
Plain-language summary
Research on the benefits of apple cider vinegar has tended to focus on its hypoglycemic effects and lipid profile changes during long-term consumption, without exploring its acute effects on oxidative stress during short-term consumption. Therefore, this study aimed to determine whether apple cider vinegar consumption affects postprandial plasma MDA levels in obese adults. The hypothesis of this study is that apple cider vinegar consumption has an acute effect on changes in postprandial plasma MDA levels in obese adult subjects.
Subject criteria are adults aged 19-59 years; obese nutritional status; based on a BMI of ≥ 25.0 kg/m² (according to the Asia-Pacific classification); in good general health. Exclusion criteria include pregnancy, breastfeeding, and menopause; consuming alcohol; intolerance to apple cider vinegar or fermented products.
This preliminary study, a parallel, randomized, open-label, controlled clinical trial, compared two groups: a control group receiving a standard diet without apple cider vinegar, and an intervention group receiving a standard diet with a single dose of apple cider vinegar.
Who can participate
Age range
19 Years – 59 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Adults aged 19-59 years.
. Obese, based on a BMI of ≥ 25.0 kg/m² (according to the Asia-Pacific classification).
. In good general health.
. No diagnosed chronic diseases (e.g diabetes mellitus, heart disease, kidney disease, cancer, hepatitis, or chronic infections).
. Willing to participate in the entire study and sign an informed consent form.
Exclusion criteria
. Pregnant, breastfeeding, or menopausal women.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial looked at how apple cider vinegar affects a marker of oxidative stress called malondialdehyde after eating — could you explain what malondialdehyde is and why it might matter for someone with obesity like me?
2Since this study is completed, have the results been published anywhere, and what did they actually find about whether apple cider vinegar made a meaningful difference in postprandial oxidative stress?
3Apple cider vinegar is something people can try on their own, but are there any real risks or downsides — like effects on tooth enamel, blood sugar, or medications — that I should know about before considering it?
4This trial was focused on a single acute effect after a meal, not long-term outcomes — does that limited timeframe mean we still don't know whether apple cider vinegar has any lasting benefit for oxidative stress or obesity management?
5Given that this was a short-term measurement study rather than a treatment trial, would you say there's enough evidence from research like this to make apple cider vinegar worth trying in my situation, or are there better-supported options I should focus on first?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Postprandial Plasma Malondialdehyde Levels
Timeframe: Baseline (fasting) to 3 hours postprandial