A Study to Evaluate the Use of Topical Ocular BL1332 for the Management of Postoperative Ocular P… (NCT07412496) | Clinical Trial Compass
Not Yet RecruitingPhase 2
A Study to Evaluate the Use of Topical Ocular BL1332 for the Management of Postoperative Ocular Pain Following Photorefractive Keratectomy
123 participantsStarted 2026-04
Plain-language summary
This is a multicenter, double-masked study to evaluate the use of Topical Ocular BL1332 for the management of post-operative pain after Photorefractive Keratectomy (PRK) surgery.
Who can participate
Age range
18 Years – 58 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Male or female 18 to 58 years of age, inclusive.
. Scheduled to undergo PRK surgery and considered to be a good candidate per the Investigator's discretion.
. Provide written informed consent (signed and dated informed consent form \[ICF\]) using the Institutional Review Board (IRB)-approved ICF prior to any study-related procedures.
. Able to read, understand, and voluntarily sign the ICF and, if applicable, provide written authorization per local privacy regulations.
Exclusion criteria
. Women of childbearing potential or non-vasectomized males with partners of childbearing potential are not eligible unless they are using an effective method of contraception and agree to use an effective method of contraception until at least 30 days after study treatment.
. Participation in a clinical trial within 30 days prior to Screening.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this is a Phase 2 trial for BL1332 eye drops, what does that mean for how much is already known about whether this treatment is safe and effective for pain after PRK surgery?
2This trial hasn't started recruiting yet — given my situation and timing for PRK surgery, is it realistic to wait and see if I might be eligible, or would it make more sense to plan around standard pain management options now?
3What are the currently approved or standard ways to manage pain after PRK surgery, and how do they compare to what this experimental eye drop is trying to do?
4If I were to eventually participate in a trial like this, would I be randomized to receive BL1332 or possibly a placebo, and how would my pain be managed if I ended up in the control group?
5Are there specific aspects of my eye health history or my planned PRK procedure that might make a trial measuring postoperative ocular pain intensity a good or poor fit for me to discuss with you?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Ocular pain intensity following PRK surgery
Timeframe: Assessed at a 24-hour period following PRK surgery