Periodontal Health Profile in Multiple Sclerosis Patients (NCT07412431) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Periodontal Health Profile in Multiple Sclerosis Patients
100 participantsStarted 2026-02-03
Plain-language summary
This study aims to evaluate the periodontal status of patients with Multiple Sclerosis (MS) through clinical, microbiological, and biochemical parameters. Multiple sclerosis and periodontal diseases are both chronic inflammatory conditions that may share common immunopathological pathways. The primary objective is to investigate the relationship between MS and periodontal health by comparing clinical measurements with the microbial composition and biochemical markers found in saliva samples of patients followed by the Neurology Department.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria (Test Group):
* Voluntarily agreeing to participate in the study.
* Being over 18 years of age.
* Diagnosed with Multiple Sclerosis (MS) according to the 2017 McDonald criteria.
* Being able to communicate clearly and effectively.
Inclusion Criteria (Control Group):
* Voluntarily agreeing to participate in the study.
* Being over 18 years of age.
* Not having a diagnosis of Multiple Sclerosis (MS) according to the 2017 McDonald criteria.
* Being able to communicate clearly and effectively.
Exclusion Criteria (Test Group):
* Being under 18 years of age.
* Patients whose MS diagnosis is not yet definitive.
* Being pregnant or in the lactation (breastfeeding) period.
* Having received antibiotic treatment within the last 3 months.
* Having received periodontal treatment within the last 6 months.
* Patients undergoing radiotherapy or chemotherapy.
Exclusion Criteria (Control Group):
* Being under 18 years of age.
* Being diagnosed with Multiple Sclerosis (MS) according to the 2017 McDonald criteria.
* Being pregnant or in the lactation (breastfeeding) period.
* Having received antibiotic treatment within the last 3 months.
* Having received periodontal treatment within the last 6 months.
* Patients undergoing radiotherapy or chemotherapy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.