Mastication, Cognition, and Nutritional Status in Multiple Sclerosis (NCT07411924) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Mastication, Cognition, and Nutritional Status in Multiple Sclerosis
86 participantsStarted 2026-03-01
Plain-language summary
The aim of this study is to investigate the relationship between chewing function and cognitive functions, disease severity, and nutritional status in individuals diagnosed with Multiple Sclerosis
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Being 18 years of age or older
Exclusion Criteria:
* Having a neurological or systemic disease other than Multiple Sclerosis that may affect chewing function
* Inability to provide adequate communication or cooperation due to psychiatric disorders
* Not being diagnosed with Multiple Sclerosis
* Not volunteering to participate in the study
* Presence of severe problems preventing questionnaire administration (visual and/or hearing impairments)
* History or presence of psychiatric and/or other neurological disorders
* Presence of severe neurological findings that may negatively affect cognitive performance (e.g., severe optic neuritis)
* Use of medications affecting cognitive functions
* Alcohol or substance use
* Having experienced a relapse within the last month
* Having received corticosteroid treatment within the last month
* History of stroke, head and neck cancer, or rheumatic diseases that may affect swallowing and chewing performance
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Expanded Disability Status Scale (EDSS)
Timeframe: Baseline
2
Montreal Cognitive Assessment (MoCA)
Timeframe: Baseline
3
Turkish version of the Eating Assessment Scale (T-EAT-10)
Timeframe: Baseline
4
Dysphagia in Multiple Sclerosis (DYMUS)
Timeframe: Baseline
5
Test of Masticating and Swallowing Solids (TOMASS)