Active — Not RecruitingNot Applicable

Hyaluronic Acid and Amino Acid Combination Versus Exercise for Chronic Lateral Epicondylitis

Turkey (Türkiye)60 participantsStarted 2025-12-01

Plain-language summary

This retrospective, controlled clinical study aims to evaluate the effectiveness of a targeted biological support injection containing a hyaluronic acid and amino acid combination in patients with chronic lateral epicondylitis (tennis elbow). Medical records will be reviewed to compare outcomes between patients treated in routine clinical practice with a 3-dose injection regimen (weeks 0, 2, and 4) plus a home exercise program and those treated with a home exercise program alone. Key outcome measures include pain intensity (VAS), functional status (PRTEE), grip strength, and pressure pain threshold.

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged between 18 and 70 years. * Patients diagnosed with Lateral Epicondylitis (LE). * Presence of symptoms persisting for 6 weeks or longer. * Patients who were treated with either a 3-dose protocol of Hyaluronic Acid + Amino Acid injection combined with a home exercise program, or a home exercise program alone. Exclusion Criteria: * History of rheumatic disease. * History of malignancy. * Presence of radiculopathy or neuropathy. * Presence of peripheral circulatory disorders. * Congenital or acquired upper extremity deformities. * History of coagulopathy or current use of warfarin therapy. * Presence of prosthesis, metal implant, or internal fixator in the elbow region.

What they're measuring

Change in Pain Intensity (VAS)

Timeframe: Baseline, Week 4, and Month 3

Trial details

NCT IDNCT07410663

SponsorSivas State Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-05-01