Sensory Stimulation as a Driver of Diet-induced Thermogenesis (NCT07409025) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Sensory Stimulation as a Driver of Diet-induced Thermogenesis
Switzerland24 participantsStarted 2026-06-15
Plain-language summary
This study aims to assess the influence of sensory stimulation on diet-induced energy expenditure by way of a clinical cross-over trial in 24 healthy participants either receiving a meal bolus with (orally) and without sensory stimulation (nasogastric-tube).
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* healthy volunteers of any gender
* BMI between 18-25 kg/m2
* age between 18 and 40 years
Exclusion Criteria:
* concomitant medication except for prescription free analgetics (paracetamol, NSAIDs) and oral contraceptives
* clinically significant concomitant disease states (e.g. renal failure, hepatic dysfunction, cardiovascular disease, diabetes mellitus),
* allergy to local anaesthetic or any of the study meal ingredients
* known or suspected non-compliance, drug or alcohol abuse
* smoker / habitual tobacco use
* habitual excessive alcohol consumption
* inability to follow the procedures of the study
* participation in another study with investigational drug within the 30 days preceding and during the present study
* previous enrolment into the current study
* enrolment of the investigator, his/her family members, employees and other dependent persons
* uncontrolled hypo- or hyperthyroidism
* pregnancy or lactation
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Diet-induced energy expenditure
Timeframe: data will be collected from baseline (30 minutes before meal bolus administration) up to 300 minutes post-administration, divided into five segments: four 30-minute intervals and one 75-minute interval.