CompletedNot Applicable

Effect of Injectable Platelet Rich Derivatives on Orthodontic Canine Retraction

Yemen21 participantsStarted 2024-05-30

Plain-language summary

This study evaluated the effect of injectable platelet-rich derivatives on the rate of orthodontic canine retraction. Patients requiring orthodontic canine retraction following premolar extraction were enrolled and divided into three groups using a split-mouth design. Injectable platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) were applied to compare their effects on the rate of tooth movement. The outcomes were assessed by measuring the amount of canine retraction over time.

Who can participate

Age range17 Years – 29 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy individuals aged 17-29 years (mean age 24 ± 6 years) * Diagnosis of Class I bimaxillary protrusion or Class II division 1 requiring first premolar extractions * Full permanent dentition * Good oral hygiene * Non-smokers * Not taking medications affecting bone metabolism (e.g., bisphosphonates) Exclusion Criteria: * Pregnancy or breastfeeding * Contraindications to platelet therapies (e.g., platelet dysfunction) * Severe malocclusion unsuitable for fixed appliances * Dental anomalies (size/shape) * Systemic syndromes

What they're measuring

Rate of Orthodontic Canine Retraction

Timeframe: From baseline (initiation of orthodontic canine retraction) until completion of canine retraction, assessed monthly for up to 4 months.

Trial details

NCT IDNCT07408895

SponsorSana'a University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-05

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