the Efficacy of Hyperbaric Oxygen on Acute Ankle Sprain (NCT07405281) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
the Efficacy of Hyperbaric Oxygen on Acute Ankle Sprain
208 participantsStarted 2026-03
Plain-language summary
Investigators recruited 208 patients with acute ankle sprain who were from the Rehabilitation Department of the Second Affiliated Hospital of Zhejiang University, School of Medicine from January 2026 to November 2028. Perform the improvement in AOFAS scores and Baird-Jackson ankle scores study and Rehabilitation assessments followed up after 3 years.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Unilateral ankle sprain;
* Swelling, bruising, and pain at the site of the sprain;
* Injury occurring within 72 hours;
* MRI examination clearly shows ligament damage.
Exclusion Criteria:
* X-ray shows ankle fracture;
* Ankle has skin lesions or skin diseases;
* History of lower limb and pelvic surgery;
* Obvious neurological or psychiatric disorders that may interfere with assessment;
* Severe ligament injuries or joint instability requiring surgical treatment;
* Previous ankle injuries, persistent pain or functional limitations;
* Pneumothorax, severe emphysema, active bleeding, or other diseases with contraindications for hyperbaric oxygen therapy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
AOFAS score
Timeframe: 3 years
2
Baird-Jackson ankle score
Timeframe: 3 years
Trial details
NCT IDNCT07405281
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University