Active — Not RecruitingPhase 1

A Study of MK-7240 in Healthy Participants (MK-7240-009)

Australia330 participantsStarted 2026-03-05

Plain-language summary

The goal of this study is to learn what happens to MK-7240 in a healthy person's body over time (pharmacokinetic or PK study). Researchers also want to learn about the safety of MK-7240 and if people tolerate it.

Who can participate

Age range

18 Years – 55 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria The main inclusion criteria include but are not limited to the following: * Has a body-mass index (BMI) between 18 and 32 kg/m\^2 Exclusion Criteria The main exclusion criteria include but are not limited to the following: * Has a history of more than 1 episode of herpes zoster infection or history of disseminated herpes zoster infection * Has a history of or current active tuberculosis (TB) infection or history of latent TB that was not fully treated

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Area Under the Concentration-Time Curve from Time 0 to Infinity (AUC0-Inf) of Tulisokibart

Timeframe: At designated timepoints up to 14 weeks

Area Under the Concentration-Time Curve from Time 0 to Last (AUC0-Last) of Tulisokibart

Timeframe: At designated timepoints up to 14 weeks

Maximum Plasma Concentration (Cmax) of Tulisokibart

Timeframe: At designated timepoints up to 14 weeks

Trial details

NCT IDNCT07405177

SponsorMerck Sharp & Dohme LLC

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2026-09-03

View on ClinicalTrials.gov More Healthy trials

Who can participate

Age range

18 Years – 55 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Area Under the Concentration-Time Curve from Time 0 to Infinity (AUC0-Inf) of Tulisokibart

Timeframe: At designated timepoints up to 14 weeks

Area Under the Concentration-Time Curve from Time 0 to Last (AUC0-Last) of Tulisokibart

Timeframe: At designated timepoints up to 14 weeks

Maximum Plasma Concentration (Cmax) of Tulisokibart

Timeframe: At designated timepoints up to 14 weeks