PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation (NCT07400068) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation
Turkey (Türkiye)88 participantsStarted 2026-03-01
Plain-language summary
This prospective observational study aims to evaluate the clinical outcomes of patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD).
In routine clinical practice, some patients receive an additional transforaminal anterior epidural steroid injection during the same session without an extra puncture. This study will prospectively follow patients who receive PLDD alone and those who receive PLDD combined with epidural steroid injection.
Pain intensity, functional status, analgesic use, need for additional interventions, and complications will be assessed over time. The results may help to clarify whether adding epidural steroid injection to PLDD improves clinical outcomes in patients with lumbar disc herniation.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Age 18 years and older
Diagnosis of single-level lumbar disc herniation confirmed by magnetic resonance imaging (MRI)
Presence of radicular leg pain refractory to conservative treatment
Undergoing routine percutaneous laser disc decompression (PLDD) as part of standard clinical care
Ability to provide informed consent
Exclusion Criteria:
Multilevel lumbar disc herniation
Extruded or sequestered disc herniation
Severe spinal canal stenosis or spinal instability
Previous lumbar spine surgery at the affected level
Active infection or systemic inflammatory disease
Coagulopathy or use of anticoagulant therapy contraindicating intervention
Pregnancy
Inability to complete follow-up assessments
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.