CompletedNot Applicable

Theta Burst Stimulation in the Management of Methamphetamine Use Disorder in Indonesia

Indonesia22 participantsStarted 2025-10-19

Plain-language summary

Methamphetamine use disorder (MUD) remains a major public health concern in Indonesia, with limited effective treatment options and high relapse rates. Theta Burst Stimulation (TBS) has emerged as a promising adjunctive intervention for reducing craving and improving clinical outcomes. This trial aims to evaluate the efficacy and safety of TBS for MUD. A RCT of 20 subjects was conducted to evalute the efficacy and safety of TBS as an adjunctive treatment to CBT in managing MUD.

Who can participate

Age range

18 Years – 59 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Subjects aged 18-59 years old * Subjects diagnosed with methamphetamine use disorder without having undergone treatment, whether psychotherapy and/or psychopharmacological modalities * Subjects are able to read and write Exclusion Criteria: * Subjects with severe thought process disorders, impaired perception, restless condition, severe neurological disorders, history of neuromodulation, * Subjects refused to participate in the study * Subjects who are pregnant * Subjects who have radioactive implants

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Improvement in craving for methamphetamine

Timeframe: Baseline (T1), day 3 (T2), day 5 (T3), day 8 (T4), and day 10 (T5)

Improvement in craving (tonic) for methamphetamine

Timeframe: Baseline (T1), day 3 (T2), day 5 (T3), day 8 (T4), and day 10 (T5)

Improvement in clinical severity

Timeframe: Baseline (T1), day 3 (T2), day 5 (T3), day 8 (T4), and day 10 (T5)

Trial details

NCT IDNCT07399431

SponsorIndonesia University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-11-03

View on ClinicalTrials.gov More Methamphetamine Use Disorder trials

Plain-language summary

Who can participate

Age range

18 Years – 59 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Improvement in craving for methamphetamine

Timeframe: Baseline (T1), day 3 (T2), day 5 (T3), day 8 (T4), and day 10 (T5)

Improvement in craving (tonic) for methamphetamine

Timeframe: Baseline (T1), day 3 (T2), day 5 (T3), day 8 (T4), and day 10 (T5)

Improvement in clinical severity

Timeframe: Baseline (T1), day 3 (T2), day 5 (T3), day 8 (T4), and day 10 (T5)