Evaluation of the Effects of Adenoidectomy and Adenotonsillectomy on Voice in Children (NCT07399041) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Evaluation of the Effects of Adenoidectomy and Adenotonsillectomy on Voice in Children
Turkey (Türkiye)36 participantsStarted 2026-02
Plain-language summary
This prospective study aims to evaluate the effects of adenoidectomy and adenotonsillectomy on voice and speech functions in children. Changes in voice quality and resonance may occur after the removal of adenoid and tonsillar tissues, particularly in pediatric patients with enlarged adenoids or tonsils.
Objective voice assessments, including acoustic, aerodynamic, and nasalance measurements, as well as subjective voice-related quality of life questionnaires, will be performed before surgery and at the first and third months after surgery. The results of this study are expected to help clinicians better inform families about possible voice changes following adenoidectomy and adenotonsillectomy procedures.
Who can participate
Age range
4 Years – 13 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 4-13 years
* Scheduled for primary adenoidectomy or adenotonsillectomy
Exclusion Criteria:
* Does not meet inclusion criteria
* Refuses to participate in the study
* Diagnosis of vocal cord disorders
* History of vocal cord surgery
* History of cleft palate or cleft lip
* Hearing loss requiring a hearing aid
* Chronic diseases that may impair wound healing, including: hypertension, diabetes mellitus, immunodeficiency, autoimmune diseases, rheumatologic diseases, connective tissue disorders, renal failure, liver failure, chronic heart disease
* Known bleeding diathesis
* Use of anticoagulant or antiplatelet drugs
* Upper respiratory tract infection within the last 2 weeks
* Patients undergoing revision adenoidectomy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Fundamental Frequency (F0)
Timeframe: Preoperative, 1 month postoperative, and 3 months postoperative
2
Change in Jitter Percentage
Timeframe: Preoperative, 1 month postoperative, and 3 months postoperative
3
Change in Shimmer Percentage
Timeframe: Preoperative, 1 month postoperative, and 3 months postoperative
4
Change in Harmonics-to-Noise Ratio (HNR)
Timeframe: Preoperative, 1 month postoperative, and 3 months postoperative
Trial details
NCT IDNCT07399041
SponsorGaziosmanpasa Research and Education Hospital