Not Yet RecruitingNot Applicable

Metabolic Characteristics and Prognostic Model of Acute Coronary Syndrome Complicated With Obstructive Sleep Apnea

1,200 participantsStarted 2026-02-01

Plain-language summary

Obstructive sleep apnea (OSA) significantly increases the risk of cardiovascular events in patients with acute coronary syndrome (ACS), yet the underlying metabolic mechanisms remain unclear. This study aims to analyze the metabolic characteristics of ACS patients with OSA using metabolomics based on a prospective cohort. The study intends to construct an artificial intelligence-based risk stratification model to improve prognosis prediction and facilitate precision medicine for this population.

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18-85 years. * Diagnosed with ACS, including ST-segment elevation myocardial infarction, non-ST-segment elevation myocardial infarction, and unstable angina. * Willing to participate and sign the informed consent form. Exclusion Criteria: * Cardiogenic shock or cardiac arrest. * Central sleep apnea or other types of sleep disordered breathing. * Previous or current treatment with continuous positive airway pressure. * Inability to complete polysomnography or invalid data. * Malignancy or life expectancy \< 1 year.

What they're measuring

Incidence of Major Adverse Cardiovascular and Cerebrovascular Events (MACCE)

Timeframe: 12 Months

Trial details

NCT IDNCT07398430

SponsorBeijing Hospital

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2027-12-31

Contact for this trial

Wei Gong

+86 13717676086 gongwei5180@bjhmoh.cn

View on ClinicalTrials.gov More Sleep Disordered Breathing (SDB) trials