RecruitingNot Applicable

Levothyroxine Treatment on Cardiac Function in Children With Subclinical Hypothyroidism

Egypt40 participantsStarted 2025-05-24

Plain-language summary

This study aims to evaluate the effect of the treatment with levothyroxine on cardiac function in children with subclinical hypothyroidism.

Who can participate

Age range4 Years – 15 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age from 4 to 15 years. * Both sexes. * Patients with stable elevated thyroid-stimulating hormone (TSH) ≥ 4.5 mIU/L with normal free T4 and ft3 in different measurement 4 - 6 weeks apart. Exclusion Criteria: * Overweight and obesity * Hypertension * Previous use of levothyroxine, antiepileptic drugs, or cardiac drugs within the last 6 months. * Arrhythmia. * Congenital or acquired heart disease * Liver or kidney disease * Hyperlipidemia * Diabetes * Infectious diseases * Respiratory diseases * Malignancies

What they're measuring

Assessment of left ventricle systolic function

Timeframe: 3 months post-procedure

Trial details

NCT IDNCT07393165

SponsorTanta University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05-01

Contact for this trial

Zeinab E Elshareef, MBBCH

00201001700194 zeinabibraheem26@gmail.com

View on ClinicalTrials.gov More Levothyroxine trials