CompletedNot Applicable

Comparison of Effect of Dexmedetomidine and Midazolam on Emergence Agitation

Pakistan146 participantsStarted 2025-07-01

Plain-language summary

Since the frequency of emergence agitation (EA) is relatively high in children while undergoing nasal surgery, and there is not much data available in Pakistan regarding EA in adults undergoing functional endoscopic sinus surgery (FESS). Hence there is a need to conduct this study in the local population to see the effect of dexmedetomidine and midazolam on EA. Therefore, the current study was initiated, aiming to compare the effect of dexmedetomidine and midazolam on EA in patients undergoing FESS.

Who can participate

Age range16 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Any gender * Aged 16-60 years * Undergoing elective FESS under general anesthesia Exclusion Criteria: * Patients with the presence of infection at the site of the blockage * Epilepsy, myasthenia gravis, or polio (as per history and clinical record) * Systemic illness (such as cardiac, hepatic, endocrinal or neurological) * Substance induced disorder * Psychiatric disorders * Taking medications, such as alpha 2 agonists, beta blockers' or tricyclic anti-depressants * Allergies to the medications used

What they're measuring

Effectiveness in emergence agitation

Timeframe: 90 minutes

Trial details

NCT IDNCT07392983

SponsorMuhammad Aamir Latif

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-31

View on ClinicalTrials.gov More Emergence Agitation trials