Strategy for EArly Recognition of Cancer, COPD & Heart Failure in the Emergency Department (NCT07391280) | Clinical Trial Compass
RecruitingNot Applicable
Strategy for EArly Recognition of Cancer, COPD & Heart Failure in the Emergency Department
United Kingdom17,000 participantsStarted 2026-05-25
Plain-language summary
SEARCH-ED is a research study which is running in Emergency Department (ED) of the Queen Elizabeth University Hospital. The aim of the study is to find out if using a computer programme can help doctors diagnose heart and lung problems from chest x-rays.
We want to compare how many people are diagnosed with heart or lung problems for the first time when doctors have access to the computer programme results, in comparison to when they don't.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Unconsented Use of Harrison CXR Algorithm in Emergency Department (ED):
* Frontal Chest X-Ray (CXR) (AP or PA) acquired in the Queen Elizabeth University Hospital (QEUH) ED
* Patients aged 18 or over
* Appropriate meta data (DICOM) to allow for Harrison CXR processing and secondary capture report provision.
Patient Focus Groups:
* Aged 18 or over
* Able to provide written, informed consent in English.
Clinician Focus Groups:
* Aged 18 or over
* Able to provide written, informed consent in English.
* Working as a doctor, advanced nurse practitioner or advanced clinical practitioner in ED, radiology or downstream medical specialties
* For post-implementation focus groups only, must have at least 4 months experience of working with Harrison CXR algorithm.
Diagnostic Clinic:
* Patients without terminal illness or advanced frailty
* Usual healthcare provider based in NHS GGC
Exclusion Criteria:
Applies to use of unconsented CXRs:
\- Patient has requested that they are removed from the study, or has objected to the use of AI in their routine clinical care and this has been subsequently upheld by the health board.
Applies to invitation to combined diagnostic clinic:
* Patients not available to follow up, including patients i.e. whose the patient's usual care (or onward care following index admission) is out-with NHS GGC.
* Patients who have been referred to palliative care for end-stage disease, or patients with severe frailty (i.e. bedbound) will no…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Proportion of patients identified with a confirmed new diagnosis of heart failure, based on subsequent clinical assessment and guideline-based investigation.