CompletedNot Applicable

Obesity on the Efficacy of Bilateral Tibial Nerve Stimulation

Egypt60 participantsStarted 2026-02-15

Plain-language summary

Obstructed defecation syndrome (ODS) is a common functional bowel disorder characterized by difficulty in stool evacuation. Bilateral posterior tibial nerve stimulation (BT PTNS) has emerged as a noninvasive, safe, and effective therapeutic option for functional ODS, improving symptom severity and quality of life.

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of functional obstructed defecation (Rome IV criteria). * Able to provide informed consent. * BMI ≥30 kg/m² (obese group) or BMI \<30 kg/m² (non-obese group). Exclusion Criteria: * Organic causes of constipation (e.g., colorectal cancer, inflammatory bowel disease). * Previous pelvic floor surgery. * Neurological disorders affecting bowel function. * Pregnancy or lactation. * Current use of other neuromodulation therapies.

What they're measuring

Change in symptom severity measured by the Modified Obstructed Defecation Score (MODS).

Timeframe: Within 6 weeks of treatment.

Change in quality of life measured by the Patient Assessment of Constipation Quality of Life questionnaire (PAC-QOL).

Timeframe: Within 6 weeks of treatment.

Trial details

NCT IDNCT07390682

SponsorGeneral Committee of Teaching Hospitals and Institutes, Egypt

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2026-03-25

View on ClinicalTrials.gov More Obstructed Defecation trials