The DISCOVER Study (NCT07390643) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The DISCOVER Study
United States100 participantsStarted 2026-07
Plain-language summary
The purpose of this research study is to evaluate the possible benefits of screening with an investigational, but commercially available blood test designed to detect many types of cancer.
The name of the screening blood test being studied is:
-GRAIL Galleri MCED test
Who can participate
Age range
22 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Be at least 22 years old
* Have signs and symptoms suggestive of cancer and/or have imaging related to signs and symptoms of cancer being evaluated in the Cancer Diagnostic Service clinic
Exclusion Criteria:
* Individuals diagnosed with invasive malignancy within 3 years of enrollment
* Individuals with active cancer requiring active therapeutic intervention at the time of participation (hormone therapy for breast/prostate cancer is considered acceptable and will not preclude participation)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Multi-cancer Early Detection (MCED) Positive Cancer Type
Timeframe: MCED testing will be performed at enrollment, with diagnostic resolution and cancer type determination expected within 12 months.
2
Multi-cancer Early Detection (MCED) Positive Cancer Incidence
Timeframe: MCED testing will be performed at enrollment, with diagnostic resolution and cancer type determination expected within 12 months.
3
Multi-cancer Early Detection (MCED) Positive Cancer Stage
Timeframe: MCED testing will be performed at enrollment, with diagnostic resolution and cancer type determination expected within 12 months.
4
Multi-cancer Early Detection (MCED) Undetected Cancer Type
Timeframe: MCED testing will be performed at enrollment, with diagnostic resolution and cancer type determination expected within 12 months.
5
Multi-cancer Early Detection (MCED) Undetected Cancer Incidence
Timeframe: MCED testing will be performed at enrollment, with diagnostic resolution and cancer type determination expected within 12 months.
6
Multi-cancer Early Detection (MCED) Undetected Cancer Stage