Calcium Dobesilate After Radiofrequency Ablation for Varicose Veins

Inclusion Criteria: * Age 18-70 years * Symptomatic primary varicose veins (CEAP classification C2-C4) * Great saphenous vein insufficiency confirmed by duplex ultrasound (reflux \>0.5 seconds) * Great saphenous vein diameter 5-12 mm * Scheduled for radiofrequency ablation * Able to provide written informed consent Exclusion Criteria: * History of deep vein thrombosis * Peripheral arterial disease (ABI \<0.9) * Active venous ulcer (CEAP C6) * Pregnancy or breastfeeding * Severe renal or hepatic insufficiency * Known allergy to calcium dobesilate * Use of venoactive drugs within the past 4 weeks * Current anticoagulant therapy * Previous venous intervention on the same limb * Bilateral disease requiring simultaneous treatment * Inability to comply with follow-up schedule