RecruitingNot Applicable

Management of Bone Loss in Orthopaedic Surgery Using the Masquelet Technique or Transport Nails

France250 participantsStarted 2026-04-27

Plain-language summary

This is a single-center prospective observational study comparing two techniques for reconstructing bone loss in the lower limbs. The aim of the study was to compare the results of reconstructions using the Masquelet technique with reconstructions using electromagnetic transport nails. The primary endpoint was time to bone healing. This study is the first prospective descriptive study of electromagnetic transport nails.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient ≥ 18 years * Minor patient, able to consent to data collection, with the consent of the owner(s) * Patient consulting for a medical reason involving a loss of bone substance in the lower limb in an investigating centre linked to one of these aetiologies for which a reconstruction procedure using a transport nail or Masquelet technique is envisaged: * Tumour pathologies requiring * Septic or aseptic pseudarthrosis * Traumatic pathology * Infectious pathologies Exclusion Criteria: * Patients under guardianship or curatorship, * Individuals deprived of their liberty by judicial or administrative decision, * Individuals receiving involuntary psychiatric care requiring the consent of their legal representative, * Individuals unable to express their consent, * Individuals under legal protection, * Patients with an indication for bone reconstruction using a technique other than the Masquelet technique and nail transport, * Patients not covered by a social security scheme, * Patients ineligible for bone reconstruction due to their comorbidities

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Rate of radiological consolidation

Timeframe: From enrollment to 36 months after

Trial details

NCT IDNCT07389681

SponsorUniversity Hospital, Bordeaux

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-03

Contact for this trial

Benjamin BOUYER, PROF

+335 56 79 87 18 b.bouyer@chu-bordeaux.fr

View on ClinicalTrials.gov More Critical-size Bone Defect trials