RecruitingNot Applicable

Peripheral Autonomic Block (BAP) Plus Transversus Abdominis Plane Block (TAP) for Postoperative Analgesia After Minimally Invasive Left-Sided Colorectal Resection (BAPTAP)

Brazil140 participantsStarted 2026-02-12

Plain-language summary

Effective postoperative pain management is essential for enhanced recovery after laparoscopic colorectal surgery. This randomized, controlled, double-blind trial will compare conventional postoperative analgesia (intravenous medications plus surgical wound infiltration) with a locoregional strategy combining a peripheral autonomic block (inferior mesenteric and superior hypogastric plexuses) and a transversus abdominis plane (TAP) block. We hypothesize that the combined strategy (BAPTAP) reduces pain intensity and opioid consumption in the first 48 hours after Left-Sided Colorectal Resection.

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Elective laparoscopic left-sided colorectal resection * ASA physical status I-II * Ability to understand the study and sign informed consent Exclusion Criteria: * Known allergy to study medications (e.g., local anesthetics) * Coagulation disorders * Pregnancy * Inability to understand or provide consent * Chronic pain on opioid therapy * BMI \> 35 kg/m²

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pain intensity

Timeframe: Day 0, day 1 and day 2 - From the surgical procedure up to 48 hours postoperatively

Cumulative opioid consumption

Timeframe: Day 0, day 1 and day 2 - From the surgical procedure up to 48 hours postoperatively

Pain frequency - Patient-reported outcomes via PAIN OUT (Portuguese-validated IPO)

Timeframe: Day 2 - 48 hours postoperatively

Patient-reported outcomes via PAIN OUT (Portuguese-validated IPO) - interference with activities and mood

Timeframe: Day 2 - 48 hours postoperatively

Participation - Patient-reported outcomes via PAIN OUT (Portuguese-validated IPO)

Timeframe: Day 2 - 48 hours postoperatively

Trial details

NCT IDNCT07388953

SponsorFaculdade de Ciências Médicas de Minas Gerais

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-05

Contact for this trial

MATHEUS MMMDE MEYER, MD

5531988044987 matheusww@gmail.com

View on ClinicalTrials.gov More Colorectal Cancer trials

Plain-language summary

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Pain intensity

Timeframe: Day 0, day 1 and day 2 - From the surgical procedure up to 48 hours postoperatively

Cumulative opioid consumption

Timeframe: Day 0, day 1 and day 2 - From the surgical procedure up to 48 hours postoperatively

Pain frequency - Patient-reported outcomes via PAIN OUT (Portuguese-validated IPO)

Timeframe: Day 2 - 48 hours postoperatively

Patient-reported outcomes via PAIN OUT (Portuguese-validated IPO) - interference with activities and mood

Timeframe: Day 2 - 48 hours postoperatively

Participation - Patient-reported outcomes via PAIN OUT (Portuguese-validated IPO)

Timeframe: Day 2 - 48 hours postoperatively