A Real-World Study on Effect of Hirudoid on Ecchymosis After Treatment of Crow's Feet With Botulinum Toxin Type A

Inclusion Criteria: * Adults (age ≥18 years) undergoing periorbital rejuvenation procedures with botulinum toxin type A (e.g., improvement in the appearance of moderate-to-severe lateral canthal lines) * Patients willing to participate in the study and return for the scheduled follow-up visit, be photographed as a part of the study procedures, and sign the informed consent form Exclusion Criteria: * Known allergy to Hirudoid or any components of Hirudoid * Known allergy to Botulinum toxin type A * Previous cosmetic surgery or visible scars in the treatment area * Severe atrophy or weakness in the target muscles * Use of local anesthetic prior to Botulinum toxin type A administration * Current or recent use of anticoagulant or corticosteroid therapy * Current cigarette smoker * History of clotting or coagulation disorders * History of cardiovascular, metabolic, endocrine, liver or renal diseases or any underlying medical condition that may interfere with the study procedures or assessments * Patients suffering from any psychiatric condition * Patients taking any agent (e.g., aminoglycoside antibiotics) or suffering from any disorder (e.g., myasthenia gravis, Eaton-Lambert syndrome) that may interfere with neuromuscular function * Pregnant or lactating women * Patients unwilling to be photographed or sign the informed consent form