Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults (NCT07388537) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults
United States1,000 participantsStarted 2026-07-01
Plain-language summary
Background:
Diabetes and obesity are chronic diseases. They can affect blood flow and how the body processes nutrients, and complications over time can lead to early death. Diabetes can affect children as well as adults, but the disease seems to be more severe and to progress faster when it appears in younger people. Researchers want to understand more about how diabetes and obesity develop and change over time.
Objective:
To collect data and samples regularly from people with obesity and diabetes.
Eligibility:
People aged 8 to 65 years. They must be overweight or obese; or have high blood sugar; or have problems with how their body uses food for energy.
Design:
Participants will have additional procedures during routine care visits at the NIH clinic.
Data collected for the study will include the following:
Information from the participant s medical chart will be kept for research.
Questionnaires will ask about participant s eating habits, feelings, sleep, and substance use. They will take 30 to 60 minutes. Care providers will address any issues revealed in these surveys.
Blood, saliva, urine, and stool samples will be collected. Samples may be used for genetic tests.
Data and samples will be kept for future research.
Participants may remain in the study up to 30 years.
Who can participate
Age range
8 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Age 8 years to 65 years
. Meet at least one of the following:
Exclusion criteria
. History of significant medical illnesses that the investigators feel may interfere with potential evaluations, i.e. individuals who are critically ill, unstable, or with severe organ failure that may affect/limit the endocrine evaluation and place unsustainable demands on Clinical Center or NIDDK resources.
. History of any medical, psychiatric, or social conditions which, in the opinion of the investigators, would make participation in this protocol not in the best interest of the participant.
. Inability or unwillingness of participant, parent/guardian, or LAR to provide informed consent.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is listed as 'not yet recruiting' — do you know when it's expected to open, and would it make sense for me to wait for it or focus on other options in the meantime?
2Since this study is focused on collecting data and samples rather than testing a specific treatment, what would actually happen at my visits, and would I still receive standard care for my obesity or diabetes while participating?
3Because this is a data-collection study with no listed phase, does that mean there's no experimental treatment involved, and how might that affect my decision compared to enrolling in a trial that's actively testing a new therapy?
4What kinds of samples might be collected — for example blood, tissue, or genetic material — and are there any risks or privacy considerations I should understand before agreeing to have my data used in future studies?
5Given that I have both metabolic concerns and either obesity or diabetes, would my doctor feel this type of long-term observational registry is a good fit for my situation, or is there a more immediately beneficial trial or treatment path worth exploring first?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
To collect data and samples during clinical evaluation, treatment, and follow-up of participants for use in future studies.
Timeframe: Up to 30 years
Trial details
NCT IDNCT07388537
SponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)