Mobility is a fundamental aspect of daily life, enabling individuals to participate in social, occupational, and recreational activities. Community mobility, defined as movement in environments outside the home, is particularly important for quality-of-life. Following lower limb amputation (LLA), mobility limitations are common and persistent. With rehabilitation and prosthetic training, many regain the ability to ambulate but results vary as only 25 - 58% of patients regain ambulatory ability and less than half of those who become ambulatory achieve sufficient ability to walk in community settings. As a result, \~40% of people with LLA are ambulatory but also use wheeled mobility (e.g., wheelchair, scooter) for some or all of their community mobility tasks. To date, the complementary role of wheeled and ambulatory mobility in maximizing community mobility has been overlooked, with clinical research overwhelmingly focused on assessing and improving ambulatory ability despite its impracticality for many community settings.
Age range
18 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
World Health Organization Quality of Life Brief Assessment (WHOQOL-BREF)
Timeframe: Visit 1 (Baseline) only/no repeated measures
Prosthesis Evaluation Questionnaire - Mobility subscale
Timeframe: Visit 1 (Baseline) only/no repeated measures
Locomotor Capabilities Index
Timeframe: Visit 1 (Baseline) only/no repeated measures
Modified telephone interview for cognitive status
Timeframe: Visit 1 (Baseline) only/no repeated measures
Life Space Assessment
Timeframe: Visit 1 (Baseline) only/no repeated measures
Houghton Scale
Timeframe: Visit 1 (Baseline) only/no repeated measures
World health organization disability assessment schedule 2.0 (WHODAS)
Timeframe: Visit 1 (Baseline) only/no repeated measures
Activities-specific balance confidence scale
Timeframe: Visit 1 (Baseline) only/no repeated measures
GPS Outcomes (spatial and temporal metrics of community mobility):Total Distance Traveled (m)
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
GPS Outcomes (spatial and temporal metrics of community mobility): Average movement speed (km/hr)
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
GPS Outcomes (spatial and temporal metrics of community mobility): Size of movement area (km2)
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
GPS Outcomes (spatial and temporal metrics of community mobility): Percentage of time spent outside the home
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
GPS Outcomes (spatial and temporal metrics of community mobility): Mean and median distance from home
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
GPS Outcomes (spatial and temporal metrics of community mobility): Number of locations visited
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
GPS Outcomes (spatial and temporal metrics of community mobility): Max distance from home (km)
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
GPS Outcomes (spatial and temporal metrics of community mobility): Frequency of out-of-home trips
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
GPS Outcomes (spatial and temporal metrics of community mobility): Time and distance on foot
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
activPAL Accelerometry: Daily duration (in minutes) of sitting, standing, and stepping
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
activPAL Accelerometry: Daily step count
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2
activPAL Accelerometry: Daily walking bouts stepping cadence
Timeframe: Data collected visit #1 through visit #2, data collected for 10-21 days, downloaded on Visit #2