Active — Not RecruitingPhase 4

Comparison of Efficacy of Azithromycin Alone vs Combination of Azithromycin and Probiotics in Management of Mild to Moderate Acne Vulgaris

Pakistan60 participantsStarted 2025-10-12

Plain-language summary

The Goal of this Clinical trial is to compare the efficacy of oral azithromycin alone with combination therapy of oral azithromycin and probiotics to see is there any significant difference in outcome of two treatment modalities in mild to moderate acne vulgaris

Who can participate

Age range15 Years – 35 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Participants with mild to moderate acne on basis of global acne assessment scale score of 2 or 3 and with 20 to 50 total lesion count will be included. \- Exclusion Criteria: History of active localized or generalized infection History of autoimmune disease History of other facial skin diseases/ excessive facial hair or scars History of using isotretinoin or oral contraceptive pills in past 6 months History of already using antibiotics for acne treatment History of facial cosmetic procedures within last 3 months History of allergy to drugs used in study History of using drugs that may interact with azithromycin Currently pregnant or lactating women

What they're measuring

Reduction of Acne Lesion Count as per Acne Global assessment scale

Timeframe: 12 Weeks

Trial details

NCT IDNCT07384793

SponsorHayatabad Medical Complex

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2026-04

View on ClinicalTrials.gov More Acne Vulgaris II or III Degree trials