Not Yet RecruitingNot Applicable

MRI Volumetry and Diffusion Tensor Imaging in Temporal Lobe Epilepsy

78 participantsStarted 2026-04-01

Plain-language summary

This works aims at evaluating the diagnostic performance of combined MRI Volumetry, Diffusion tensor imaging and Conventional MRI in lateralizing the epileptogenic focus in patients with temporal lobe epilepsy and correlate these findings with clinical outcome.

Who can participate

Age range12 Years – 50 Years

SexALL

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Inclusion Criteria: * Patients with different age groups having temporal lobe epilepsy diagnosed by EEG with no detected structural brain lesion by conventional MRI other than mesial temporal sclerosis. Exclusion Criteria: * Contraindications for MRI as claustrophobia, cardiac pacemaker and non-compatible metallic devices. * Patients with suboptimal images or techniques. * Post-operative and post-head traumatic cases.

What they're measuring

Hippocampal mean diffusivity (MD) values measured by diffusion tensor imaging (DTI) in patients with temporal lobe epilepsy and non-epileptic control subjects.

Timeframe: Baseline

Trial details

NCT IDNCT07384351

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-04-30

Contact for this trial

Reem Mohamed Saad, Assistant lecturer

+201014122696 saadreem89@gmail.com

View on ClinicalTrials.gov More Temporal Lobe Epilepsy (TLE) trials