NeoAdjuvant ChemoTherapy With KELIM Guided Interval vs. Delayed Interval Debulking Surgery

Inclusion Criteria: * Age 18 - 85 years old * Histologically proven epithelial ovarian cancer, fallopian tube carcinoma, or primary peritoneal carcinoma, high grade serous or endometrioid * ECOG Performance status 0 - 1 * Documented International Federation of Gynecologic Oncology (FIGO) 2014 stage IIIB, IIIC or IVA unfit and/or with unresectable disease for complete primary debulking surgery (preferably triaged by "Fagotti" diagnostic laparoscopy) * HIPEC is an option after IDS or DIDS * Sufficiently good bone marrow, liver, and renal function to receive chemotherapy and subsequently undergo surgery Exclusion Criteria: * Pregnancy * Synchronous malignancies at the time of diagnosis or in the 3 years prior to starting the study treatment * Comorbidities that may contraindicate surgery or chemotherapy as planned per protocol * Mucinous, clear-cell, carcinosarcoma or low-grade serous adenocarcinoma histological subtypes * Stable disease or progression of disease (preferably triaged by "Fagotti" diagnostic laparoscopy) after 6 cycles of NACT, before DIDS.