Effect of Different Products to Support Plaque Control During Daytime (NCT07382310) | Clinical Trial Compass
CompletedNot Applicable
Effect of Different Products to Support Plaque Control During Daytime
Australia20 participantsStarted 2020-09-18
Plain-language summary
The goal of this clinical trial is to test if the additional use of different commercially available products for a better breath and plaque reduction, taken during daytime between morning and evening tooth brushing, can reduce the plaque formation of participants during the day.
The tested products were:
* Listerine Total Care mouth rinse without alcohol.
* Oral B Pro-Health Multi-Protection Mouth Rinse refreshing mint without alcohol.
* Colgate total advanced pro-shield mouth rinse without alcohol.
* Listerine Go Tabs.
* Wrigley Extra White Soft Chew Peppermint chewing gum.
The main questions it aims to answer are:
Can the tested product lower the plaque formation? Can the tested product improve the mouth freshness and breath?
Researchers will compare the tested products to not using any product (controls).
Participants need to come for a screening appointment and sign a consent form at first. If they are eligible, they need to come 6 times to the clinic. On each day, they need to come twice (morning appointment at 8 a.m. and evening appointment at 4 p.m.).
In the morning, they will have teeth cleaning and recieve one of the tested products to use on that day only (after tea break and lunch break), or they will recieve no product (control day).
In the evening, participant's teeth will be stained and oral photos will be taken. They will be asked about their perciption of freshness and good breath after using the product.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age is 18 years or more.
* Generally healthy.
* All teeth (28 teeth, excluding 3rd molars) should be present.
* The absence of untreated caries, secondary caries or faulty restorations.
* No orthodontic appliances (removable or/and fixed).
* No oral lesions, no active periodontal disease (no active inflammation or bleeding).
* Not using a mouthwash or any chewing product in the last week before the beginning of the study.
Exclusion Criteria:
* Pregnancy, lactation.
* Any chronic disease including diabetes, cardiac disease and diseases of the immune system.
* Presence of signs and symptoms of an acute infection in the oral cavity.
* Any prescribed systemic or topical medication.
* Any known allergies against ingredients of the different tested products.
* Use of antibiotics in the last 3 months.
* Use of nonsteroidal anti-inflammatory drugs (NSAID) in the last 3 months.
* History of alcohol or drug abuse.
* Smokers.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.