Correlation of Oxygenation and Saturation Indices in One-Lung Ventilation (NCT07381517) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Correlation of Oxygenation and Saturation Indices in One-Lung Ventilation
Turkey (Türkiye)51 participantsStarted 2026-02-09
Plain-language summary
One-lung ventilation is commonly used during thoracic surgery but is frequently associated with impaired oxygenation and altered respiratory mechanics. Traditional oxygenation indices require arterial blood gas analysis and do not fully reflect the mechanical stress applied to the lungs.
This prospective observational study aims to evaluate the correlation between oxygenation indices and oxygen saturation indices during one-lung ventilation in adult patients undergoing elective thoracic surgery. Modified indices incorporating driving pressure and mechanical power will also be assessed.
No intervention beyond standard clinical care will be applied. The findings of this study may help clarify the clinical utility of non-invasive oxygenation indices for intraoperative monitoring during one-lung ventilation.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients aged 18 years and older
* Patients classified as ASA physical status I-III
* Patients scheduled for elective thoracic surgery requiring one-lung ventilation for at least 1 hour intraoperatively
* Patients in whom simultaneous arterial blood gas analysis and continuous SpO₂ monitoring can be performed
* Patients who have provided written informed consent
Exclusion Criteria:
* Patients undergoing emergency surgery
* Patients younger than 18 years of age
* Patients classified as ASA physical status IV or higher
* Patients with a history of previous thoracic surgery
* Patients with a body mass index (BMI) \>40 kg/m² or \<18 kg/m²
* Patients with advanced chronic lung disease (COPD stage III-IV)
* Patients with New York Heart Association (NYHA) class III-IV heart failure
* Patients undergoing surgery due to pleural effusion
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Correlation between oxygenation indices and oxygen saturation indices
Timeframe: During intraoperative one-lung ventilation
Trial details
NCT IDNCT07381517
SponsorAnkara Ataturk Sanatorium Training and Research Hospital