Not Yet RecruitingPhase 4

Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean Delivery

Egypt260 participantsStarted 2026-06-01

Plain-language summary

We hypothesize that the addition of ephedrine to norepinephrine infusion could decrease the incidence of post spinal hypotension(PSH) in parturient undergoing C.S under spinal anesthesia and minimize the changes in heart rate

Who can participate

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ASA physical status II * Age: 18 to 40 years * Undergoing Elective Lower Segment Cesarean Section under Spinal Anesthesia. Exclusion Criteria: * Uncontrolled cardiac morbidities As reduction of ejection fraction\< 60%, History (within 3months) of myocardial infarction, cerebrovascular accident, transient ischemic attacks or coronary artery disease/stents * Poorly controlled Hypertensive disorders of pregnancy * Peripartum bleeding * Coagulation disorders * Baseline systolic blood pressure (SBP) \< 100 mmHg * Refusal of patients.

What they're measuring

Incidence of post-spinal hypotension

Timeframe: Baseline (T0), just after spinal anaesthesia (T1) then every 2.5 minutes until delivery of the fetus

Trial details

NCT IDNCT07379710

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12

Contact for this trial

Mohamed AMY AMY Ollaek, Assistant Professor

+20100 659 5598 ollaekm@kasralainy.edu.eg

View on ClinicalTrials.gov More Incidence of Post-spinal Hypotension trials