Effects of Weekly Set Volume on Muscle Adaptation (NCT07379385) | Clinical Trial Compass
By InvitationNot Applicable
Effects of Weekly Set Volume on Muscle Adaptation
Brazil57 participantsStarted 2026-01-01
Plain-language summary
The progressive loss of strength and muscle mass is a natural aging process, with direct implications for functional capacity. Resistance training (RT) is considered the main intervention to counteract this decline. Although the RT guidelines are well established, the ideal weekly set volume to maximize strength and hypertrophy gains in older adults remains unknown. The purpose of this study is to investigate the effects of different volumes of weekly sets of RT on muscle strength and hypertrophy in older adults
Who can participate
Age range
65 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age between 65 and 80 years
Exclusion Criteria:
* not having used any medication or substance that affects or improves muscle function for at least 3 months prior to the study,
* having any physical or physiological limitation that may affect the ability to perform the tests and physical training,
* not being able to understand the informed consent form and study procedures.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Maximum dynamic strength (1RM)
Timeframe: baseline and after 10 weeks of intervention
2
Maximum voluntary isometric contraction (MVIC)
Timeframe: baseline and after 10 weeks of intervention
3
Muscle hypertrophy (thickness)
Timeframe: baseline and after 10 weeks of intervention