Weak Pulse at Yang and Wiry Pulse at Yin Theory (NCT07378228) | Clinical Trial Compass
CompletedNot Applicable
Weak Pulse at Yang and Wiry Pulse at Yin Theory
China70 participantsStarted 2023-07-01
Plain-language summary
This is a clinical study to evaluate the effectiveness and explore the possible working mechanisms of a traditional Chinese herbal formula called Yixin Powder. The study focuses on patients with stable angina pectoris (chest pain) caused by coronary heart disease (CHD), who are diagnosed with a specific Chinese medicine pattern known as "qi deficiency and blood stasis," based on the "weak pulse at yang and wiry pulse at yin" theory.
The study hypothesizes that adding Yixin Powder to standard Western medication will be beneficial for these patients. To test this, participants diagnosed with this condition will be randomly assigned to one of two groups. One group will receive standard medication alone, while the other group will receive the same standard medication plus Yixin Powder. The effects of the treatments will be compared between the two groups.
Who can participate
Age range
40 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosis of CHD-induced stable angina pectoris according to Western medicine diagnostic criteria；
* Diagnosis of qi deficiency and blood stasis pattern according to TCM pattern differentiation;
* Age between 40 and 70 years, regardless of sex;
* Stable vital signs and normal liver and renal function before enrollment;
* Angina severity graded between I and III;
* Voluntary participation with signed informed consent.
Exclusion Criteria:
* Uncontrolled severe hypertension (BP ≥180/110 mmHg);
* Severe comorbid conditions involving major organs or systems, including heart, brain, liver, or kidneys;
* Known allergy to, or intolerance of, any of the study medications; (3) Presence of psychiatric disorders;
* Requirement for long-term use of medications that could interfere with study outcomes;
* Coexisting infectious diseases.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Response Rate based on Traditional Chinese Medicine (TCM) Syndrome Score Improvement
Timeframe: Assessed before treatment initiation and after 4 weeks of treatment.
2
Response Rate based on Electrocardiogram (ECG) Improvement
Timeframe: Assessed before treatment initiation and after 4 weeks of treatment.