Transcranial Electrical Stimulation for Noninvasive Study of Menopausal/Perimenopausal Symptoms

Inclusion Criteria: * Age between 40 and 60 years * Participants falling under stages -2 to +2 in the Stages of Reproductive Aging Workshop (STRAW +10) as defined below: * Early menopause transition (Stage -2): Increased variability in menstrual cycle defined as persistent difference of 7 days or more in the length of consecutive cycles. Persistence is defined as recurrence within 10 cycles of the first variable cycle. * Late menopause transition (Stage -1): Occurrence of amenorrhea of 60 days or longer. * Final Menstrual Period (Stage 0): Have undergone 12 consecutive months without a menstrual period, not due to other medical causes. * Early Postmenopause (Stage +1): 5-8 years after final menstrual period. * Late Postmenopause (Stage +2): \>8 years after final menstrual period. * Participants having frequent hot flashes (at least once a day). Exclusion Criteria: * Disorders that may mask or coincide with menopause and peri-menopause, such as: Primary Ovarian Insufficiency, Thyroid disease (Hyper/hypothyroidism), Hyperprolactinemia, Cushing's syndrome, Endometrial/Ovarian Cancer, Polycystic Ovary Syndrome (PCOS), Functional hypothalamic amenorrhea * Concurrent drugs: * GnRH agonist/antagonist * Tamoxifen/aromatase inhibitors * Other conditions: Recent hematoma (\<48 hours), History of hemorrhagic disorders (any platelet disorder (ITP, TTP, HUS, Glanzmann thrombasthenia), Hemophilia A/B, history of arterial insufficiency, any prior history of malignancy, current pregnancy,…