Research on Timing of Liraglutide Therapy in Patients With Obesity After Metabolic Surgery (NCT07374445) | Clinical Trial Compass
CompletedPhase 4
Research on Timing of Liraglutide Therapy in Patients With Obesity After Metabolic Surgery
China100 participantsStarted 2023-09-01
Plain-language summary
The goal of this clinical trial is to compare the weight loss and metabolic benefit in patients remaining obesity at 6 months after metabolic surgery. The main questions it aims to answer are:
\[primary hypothesis 1\] Whether liraglutide benefits weight loss when it is initiated early after metabolic surgery.
\[primary hypothesis 2\] Whether weight loss and metabolic benefits are greater when linaglutide is initiated in patients who are obese at 6 months after metabolic surgery
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients 6 months after metabolic surgery;
* 18 years ≤ age ≤ 65 years;
* Body Mass Index (BMI) ≥ 28 kg/m\^2
Exclusion Criteria:
* allergy to liraglutide, severe hepatic or renal impairment (eGFR \<60 mL/min/1.73 m² or ALT/AST ≥3× ULN)
* history of medullary thyroid carcinoma, MEN-2 or other malignancies
* pancreatitis or severe gastrointestinal disease, pregnancy or lactation
* use of anti-obesity drugs or other interventional trials within 3 months or major uncontrolled illness
* Patients were discontinued if withdrawn, intolerant, lost to follow-up, or developed severe adverse events.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in %TWL from baseline to endpoint across patient groups
Timeframe: 48 weeks from enrollment
Trial details
NCT IDNCT07374445
SponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School