Not Yet RecruitingNot Applicable

Effects of Dietary Supplements on Nail and Hair Health

90 participantsStarted 2026-01-01

Plain-language summary

This is a research study conducted by Standard Process, Inc. and the University of North Carolina and Chapel Hill Nutrition Research Institute, which aims to evaluate the effectiveness of nutritional supplementation in improving the health of fingernails and hair. We value your participation.

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Healthy female and male adults who are 18 to 75 years of age (inclusive)
✓. Display longitudinal (vertical) nail ridges in the absence of other nail abnormalities
✓. No cosmetic nail treatments that would mask the natural appearance of the nail plate in the past 6 months (i.e., manicure procedures that smooth the nail surface, nail polish)
✓. In good general health (no uncontrolled diseases or conditions) as deemed by the investigator and is able to consume the study product
✓. Individuals with childbearing potential must agree to practice an acceptable form of birth control for a certain timeframe prior to the first dose of study product and throughout the study, including:
✓. use for at least 3 months prior to the first dose of study product: hormonal contraceptives including oral contraceptives, hormone birth control patch (e.g., Ortho Evra), vaginal contraceptive ring (e.g., NuvaRing), injectable contraceptives (e.g., Depo-Provera, Lunelle), or hormone implant (e.g., Norplant System), or intrauterine devices (e.g., Mirena); or
✓. use for at least 1 month prior to the first dose of study product: double-barrier method, non-hormonal intrauterine devices (i.e., copper), or complete abstinence from sexual intercourse that may result in pregnancy; or
✓. vasectomy of partner at least 6 months prior to the first dose of study product.

Exclusion criteria

✕. Individuals who are lactating, pregnant or planning to become pregnant during the study as confirmed at the baseline visit (Visit 2)
✕. Individuals who have applied cosmetic/topical treatments to fingernails in the past 6 months (i.e., manicures with nail plate filing, nail polish)
✕. Individuals who display nail abnormalities indicative of a health condition affecting nail appearance or have been diagnosed with a disease affecting nails (i.e., thickening, discoloration, horizontal nail ridges \[Beau's lines\])
✕. Have a known sensitivity, intolerability, or allergy to any of the study products or their excipients
✕. Currently has COVID-19 or tests positive for COVID-19 within 28 days prior to baseline visit
✕. Individuals opposed to consuming animal products
✕. Have a history of uncontrolled hypertension (140/90 or greater mmHg), kidney dysfunction or disease (dialysis or renal failure), hepatic impairment or disease.

What they're measuring

Determine the effects of test products (TP1/2) versus active control (AC) on numbers and severity of longitudinal (vertical) nail ridges

Timeframe: 6 months

Determine the effects of TP1/2 versus AC on nail biostructure and biochemical composition after 6 months of supplementation

Timeframe: 6 months

Trial details

NCT IDNCT07373574

SponsorStandard Process Inc.

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2027-05-01

Contact for this trial

Voruganti

704-250-5034 vorugantiresearch@unc.edu

View on ClinicalTrials.gov More Nutrient Intake trials