Clinical Study on the Early Bactericidal Activity of Contezolid Against Mycobacterium Abscessus Disease

Inclusion Criteria: * Male or female aged between 18 and 65 years old; * Weight ranging from 40 kg to 90 kg; * At least one positive sputum culture for Mycobacterium abscessus within 6 months prior to screening, and one positive sputum culture for Mycobacterium abscessus with molecular species identification during the screening period within 1 month prior to the study; * Voluntary participation in this study and signing of the informed consent form; (5) Male and female participants must use effective contraception during the study and for 1 month after the study ends. Exclusion Criteria: * Patients who have been on long-term corticosteroid therapy or taking immunosuppressants within 90 days prior to screening; * Pregnant women, postpartum women, and lactating patients; * Patients with a history of bedaquiline allergy or known hypersensitivity, or a history of severe adverse reactions; * Patients with evidence of bedaquiline resistance; * Patients deemed unsuitable for participation in this study by the investigator's assessment; * Patients whom the investigator believes participation in this study would harm their health, or who are unlikely to comply with the scheduled visits and assessments as outlined in the protocol, and therefore are not suitable for participation in this study.