This study will evaluate the effect of an allogeneic adipose tissue extract on wound healing and scar maturation. Thirty adult patients scheduled for skin graft surgery will be enrolled. Each patient will have two skin graft donor sites harvested. One skin graft donor site wound will be treated topically with the adipose tissue extract, applied immediately after harvesting and reapplied on Day 3, while the other skin graft donor site wound will receive standard care. The main outcome is the time to complete epithelialization of the wound, as confirmed by investigators and independent reviewers. Secondary measures include wound characteristics, scar formation and scar quality, and monitoring of adverse events, such as wound deterioration.
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Clinical evaluation
Timeframe: Day 3, Day 7, Day 14, Day 60
The number adverse events, including deterioration of the wounds during the study.
Timeframe: Day 3, Day 7, Day 14, Day 60
Clinical evaluation
Timeframe: Day 3, Day 7, Day 14
Clinical imaging
Timeframe: Post op, Day 3, Day 7, Day 14, and Day 60
Clinical evaluation
Timeframe: Day 60