CompletedNot Applicable

Is Cryotherapy Beneficial After Surgical Removal of Impacted Lower Third Molars?

20 participantsStarted 2017-01-15

Plain-language summary

The present study aimed to investigate the effects of cryotherapy on postoperative parameters (pain intensity, edema, trismus, and the quality of life) after lower third molar extraction. Patients underwent bilateral extraction of mandibular third molars in a single surgical procedure. Cryotherapy was applied to one side using facial ice packs, while no cryotherapy was performed on the contralateral side. Surgical procedures, postoperative instructions, and prescribed medications were identical for both sides. Consequently, the side treated with ice packs exhibited lower pain intensity, shorter pain duration, and reduced use of rescue medication.

Who can participate

Age range

18 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * Indication for bilateral surgical removal of mandibular third molars in similar positions * Absence of systemic comorbidities * Absence of local inflammatory processes * Absence of local infectious processes * No history of allergy to the prescribed medications * No chronic use of antibiotics, anti-inflammatory drugs, corticosteroids, and/or analgesics Exclusion Criteria * Use of medications other than those prescribed by the surgeon * Failure to provide the required data

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Effects of cryotherapy on postoperative pain intensity after lower third molar extraction - using a visual analog scale.

Timeframe: 7 days

Evaluate the effects of cryotherapy on postoperative edema after lower third molar extraction - using the mean of three linear facial measurements

Timeframe: 7 days

Evaluate the effects of cryotherapy on postoperative trismus after lower third molar extraction - measuring maximum mouth opening

Timeframe: 7 days

Evaluate the effects of cryotherapy on postoperative quality of life after lower third molar extraction - using a questionnaire adapted from the Oral Health Impact Profile-14 (OHIP-14)

Timeframe: 7 days

Trial details

NCT IDNCT07370870

SponsorHenrique Tedesco

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-07-30

View on ClinicalTrials.gov More Cold Therapy trials

Plain-language summary

Who can participate

Age range

18 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Effects of cryotherapy on postoperative pain intensity after lower third molar extraction - using a visual analog scale.

Timeframe: 7 days

Evaluate the effects of cryotherapy on postoperative edema after lower third molar extraction - using the mean of three linear facial measurements

Timeframe: 7 days

Evaluate the effects of cryotherapy on postoperative trismus after lower third molar extraction - measuring maximum mouth opening

Timeframe: 7 days

Evaluate the effects of cryotherapy on postoperative quality of life after lower third molar extraction - using a questionnaire adapted from the Oral Health Impact Profile-14 (OHIP-14)

Timeframe: 7 days