CompletedNot Applicable

Effect of Initiation of Veno-venous ECMO on Urine Output and Acute Kidney Injury

Belgium76 participantsStarted 2025-12-01

Plain-language summary

With this study, the investigators want to find out whether the use of a "lung machine" (extracorporeal membrane oxygenation (ECMO)) togethet with giving the lungs "rest" (by minimizing ventilary support) in people with severe pneumonia has an effect on how well the kidneys work. The investigators will use information that was already collected while patients were staying in the intensive care unit. Patients do not need to do anything additional or undergo any additional procedures for this study.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18 years or older * Admission to the Intensive Care Unit (ICU) of Ghent University Hospital * Treatment with veno-venous extracorporeal membrane oxygenation (VV- ECMO) * ICU admission between 1 January 2019 and 31 December 2023 Exclusion Criteria: * Receipt of renal replacement therapy (RRT) prior to ICU admission * Patients already receiving VV-ECMO at the time of admission to the ICU of Ghent University Hospital (i.e., patients referred from another hospital on VV-ECMO) * Patients who received VV-ECMO immediately upon admission to the ICU of Ghent University Hospital

What they're measuring

Difference in urine output (staged by KDIGO criteria) 6h before and after start veno-venous ECMO and ultraprotective ventilation

Timeframe: 6 hours

Trial details

NCT IDNCT07368868

SponsorUniversity Hospital, Ghent

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-12-01

View on ClinicalTrials.gov More ARDS (Acute Respiratory Distress Syndrome) trials