RecruitingNot Applicable

Prevalence of Airway Closure

Argentina75 participantsStarted 2025-09-01

Plain-language summary

The primary objective of this study is to describe the prevalence of airway closure during the total support phase of invasive mechanical ventilation in subjects admitted to an intensive care unit (ICU). The secondary objective is to analyze whether there are clinical-demographic and/or ventilatory characteristics associated with the presence of airway closure.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients over 18 years of age * Requiring invasive mechanical ventilation within 48 to 72 hours after orotracheal intubation * Hemodynamically stable (mean arterial pressure greater than 60 mmHg and/or norepinephrine less than 0.5 mcg/kg/min) * Without respiratory muscle effort Exclusion Criteria: * Neumothorax * Bronchopleural fistula * Clinical evidence or suspicion of elevated intracranial pressure (greater than 18 mmHg)

What they're measuring

airway closure

Timeframe: first 72 hours after intubation

Trial details

NCT IDNCT07368491

SponsorRomina Belen Mattei

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-10

Contact for this trial

Romina B Mattei

+541140485216 rominabelenmattei@gmail.com

View on ClinicalTrials.gov More To Determine the Annual Prevalence of Airway Closure trials