CompletedPhase 3

Comparison Between Two Techniques in Treatment of Female Stress Urinary Incontinence

Egypt40 participantsStarted 2024-07-10

Plain-language summary

compare the therapeutic effect of periurethral injection of autologous platelet-rich plasma (PRP) and injectable platelet rich fibrin (i-PRF) in treatment of female stress urinary incontinence and comparing the need for re-injection in the two groups.

Who can participate

Age range30 Years – 75 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female patients with primary symptoms of SUI confirmed by patient's medical history and clinical examination, including a focused incontinence evaluation * Age range of 30-75 years * Females unfit for surgery * Females with SUI recurrence after previous surgical procedure by suburethal sling * Females refusing surgical interventions Exclusion Criteria: * Residual urine volume exceeding 100 cc after excretion * Evidence of detrusor over-activity on the urodynamic test * Active urinary tract or vaginal infection * Malignancies of the genitourinary system * Patients with genitourinary fistula or urethral diverticulum

What they're measuring

changes in the severity of SUI measured by Incontinence Impact Questionnaire (IIQ7)

Timeframe: baseline and three and six months follow up

Trial details

NCT IDNCT07366762

SponsorKafrelsheikh University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-01

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