Not Yet RecruitingNot Applicable

Kidney Transplant Immunosuppressive Therapy Adherence Trial (KITE)

Turkey (Türkiye)60 participantsStarted 2026-01-05

Plain-language summary

This randomized controlled interventional study aims to evaluate the effect of structured education and telephone counseling on immunosuppressive medication adherence among kidney transplant recipients. Poor adherence to immunosuppressive therapy after kidney transplantation is a major risk factor for acute rejection, graft loss, and increased morbidity. Education and behavioral support interventions delivered by nurses may improve medication understanding, adherence behaviors, and self-management skills. In this trial, 60 participants will be randomly assigned to either an intervention group receiving individualized education, an immunosuppressive medication adherence booklet, and scheduled telephone counseling sessions, or a control group receiving routine clinical care. Adherence will be assessed using the Immunosuppressive Medication Adherence Scale and biological monitoring through tacrolimus level variability over 8 weeks. Additional outcomes include changes in medication knowledge scores based on pre-test and post-test assessments. The study will contribute evidence regarding whether nurse-led telephone counseling and structured education can enhance adherence, improve clinical follow-up, and support long-term graft success in kidney transplant patients.

Who can participate

Age range

18 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult kidney transplant recipients aged 18 years or older * At least 1 month post-kidney transplantation * Able to provide informed consent * Cognitively intact and oriented to person, place, and time * Able to communicate via telephone * Voluntarily willing to participate in the study Exclusion Criteria: * Under 18 years of age * Severe cognitive impairment preventing participation * Inability to communicate effectively (hearing or speech limitations without support) * Patients who do not meet the post-transplant time threshold (less than 1 month) * Patients unwilling or unable to participate in follow-up sessions

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Adherence Score to Immunosuppressive Medication

Timeframe: Baseline and Week 8

Trial details

NCT IDNCT07364123

SponsorUniversity of Gaziantep

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05-15

Contact for this trial

Tugba ALBAYRAM Study Coordinator / Sub-Investigator, Research Assistant Dr.

+905548758383 tugbaalbayram@gmail.com

View on ClinicalTrials.gov More Kidney Transplantation trials