CompletedNot Applicable

Assessment of Brain Oxygen Drops During Surgery and Related Risk Factors for Cognitive Problems After Heart Surgery

Turkey (Türkiye)102 participantsStarted 2023-03-01

Plain-language summary

This study examines whether decreases in brain oxygen levels during cardiac surgery are linked to postoperative cognitive dysfunction and identifies other factors that may increase the risk of cognitive impairment.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Planned elective CPB surgery * Provision of written informed consent * Absence of communication barriers that could interfere with preoperative and postoperative MMSE assessment * No history of cerebrovascular disease * Preoperative MMSE score ≥24 * Education level of at least high school * Absence of any frontal deformity that could hinder NIRS monitoring Exclusion Criteria: * Preoperative use of antipsychotic or antidepressant medications * Emergency cardiac surgery indication * Presence of ≥50% carotid artery stenosis

What they're measuring

Incidence of Postoperative Cognitive Dysfunction (POCD)

Timeframe: Baseline (preoperative, before surgery) and postoperative day 4, postoperative day 7, and postoperative day 30.

Trial details

NCT IDNCT07361068

SponsorBursa Yuksek Ihtisas Training and Research Hospital

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2024-03-01

View on ClinicalTrials.gov More Cognitive Dysfunction, Postoperative trials